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Science Sparks @ ACTREC
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 25 May 2026 |
Vol. No. 15 ; Issue No.736 |
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Publications
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1. Puppalwar A, Engineer R, Jha AK, Gudi S, Krishnartry R, Nayak P, Agarwal JP, Goda JS (2026). MRI based radiomics as an imaging biomarker for locally advanced carcinoma rectum: Predicting tumor response following neoadjuvant chemoradiotherapy as an organ preservation strategy. Cancer Reports .9(5):e70574.
2. Khan UK, Goel A, Nigam S, Chaudhary N, Praveen A, Roy A, Fatima F, Sawhney DK, Dalwai A, Shendre A, Carskadon S, Bajpai A, Kapoor A, Tewari A, Chandra A, Saklani A, Dalal SN, Palanisamy N, Ateeq B (2026). DKC1 promotes colorectal cancer progression and therapy resistance by dysregulating sphingolipid biosynthesis. Nature Communications. 17(1):4406.
3. Reddy M, Mantri M, Kumar V, Bindu A, Mokhale K, Jaiswal D, Mathews S, Shankhdhar VK (2026). Feasibility of Flexor Hallucis Muscle-Based Fibula Bone Segment for Ramus Reconstruction in Head and Neck Cancers. Microsurgery. 46(4):e70245
4. Murthy V, Maitre P, Pal M, Arora A, Phurailatpam R, Sharma R, Gudipudi D, Rajappa S, Pujari L, Bandekar B, Joseph D, Kannan S, Krishnatry R, Misra A, Joshi A, Noronha V, Prabhash K, Menon S, Bakshi G, Prakash G. Bladder Adjuvant Radiotherapy: Phase III Multicenter Randomized Controlled Trial of Adjuvant Radiotherapy or Observation for Postcystectomy Muscle-Invasive Bladder Cancer. J Clin Oncol. 2026 May 21:JCO2502093 Epub ahead of print. PMID: 42166701.
Patent
Hasan SK, Maity A, Kumar R (2026). Detection of Acute Promyelocytic Leukemia or PML-RARA using CRISPR/LbCas12a system. Indian Patent Number- 590050.
Book Chapter
Dhurat O, Navyatha S, Jogipeta H, Arandkar S. (2026): Chronic Staphylococcus Infections and Cancer: Mechanisms and Treatments. In: Musini A, Kolliputi N, Yata VK.(Eds.) Staphylococcus Aureus. Pathogenesis, Drug Resistance, and Therapeutics Boca Raton; CRC Press.
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Video of the Week
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| Rising Role of Radiation Therapy in Hepatocellular Carcinoma |
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Do You Know?
In 2013, Radium Ra 223 dichloride (Xofigo), which can bind with minerals in the bone and deliver radiation directly to bone tumors, was approved by FDA to treat
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Cancer News
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Cancer cells exploit fat metabolism to survive chemotherapy
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Nature India, 21/05/2026
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The study found that a protein called DKC1 is unusually active in many colorectal cancers and is linked to poorer patient outcomes. Tumours with high DKC1 activity were more aggressive and more likely to resist FOLFOX — one of the most widely used chemotherapy treatments for colorectal cancer...
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Rerouting dead tumor debris enhances cancer immunotherapy outcomes.
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News-Medical.Net, 20/05/2026
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Broadening of immune to tumor antigens has been shown to be required for efficacy of most immunotherapy approaches for treatment of cancer. Cross training non-cDC1 cells to enhance epitope spreading presents an opportunity to develop highly targeted immunotherapy treatments....
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2026 Advanced Centre for Treatment, Research and Education in Cancer (ACTREC)
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